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Case Report
Alobar holoprosencephaly: A case report
1 Professor in Obstetrics and Gynecology Department, University Hospital Center Ibn Rochd, Casablanca 20100, Morocco
2 Resident Doctor in Obstetrics and Gynecology Department, University Hospital Center Ibn Rochd, Casablanca 20100, Morocco
3 Head of Service in Obstetrics and Gynecology Department, University Hospital Center Ibn Rochd, Casablanca 20100, Morocco
Address correspondence to:
Imane El Abbassi
Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medicine and Pharmacy, Hassan II University, 1 rue des hôpitaux, Casablanca,
Morocco
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Article ID: 100032G06MJ2023
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Jalal M, El Abbassi I, Amghar A, Lamrissi A, Bouhya S. Alobar holoprosencephaly: A case report. Edorium J Gynecol Obstet 2023;8(2):1–4.ABSTRACT
Introduction: Holoprosencephaly (HPE) is a rare brain malformation, which results from a cleavage defect of the prosencephalon. Three forms have been described as: alobar, semi-lobar, and lobar forms.
Case Report: We report a rare case of holoprosencephaly, diagnosed at the maternity of the Ibn Rochd Hospital Center in Casablanca.
Conclusion: Holoprosencephaly is secondary to a cleavage anomaly of the prosencephalon, the diagnosis is based on echotomography, computed tomography (CT) scan and nuclear magnetic resonance imaging (MRI). It is important to perform a karyotype to look for a chromosomal anomaly. Holoprosencephaly, although rare, should be recognized and diagnosed; minor forms are likely to benefit from medical replacement therapy or ventricular shunting.
Keywords: Case report, Cerebral and facial malformations, Holoprosencephaly, Ultrasound transfontanellar
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Author Contributions
Mohammed Jalal - Substantial contributions to conception and design, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Imane El Abbassi - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Ayoub Amghar - Interpretation of data, Drafting the article, Final approval of the version to be published
Amine Lamrissi - Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published
Said Bouhya - Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Mohammed Jalal et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
