Case Report


Diabetes and pregnancy with caudal dysgenesis syndrome: A rare congenital malformation about a case and review of the literature

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1 Obstetric Service of Gynaecology I, CHU HassanII, Fès, Morocco

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Andatia Malidé

Obstetric Service of Gynaecology I, CHU HassanII, Fès,

Morocco

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Article ID: 100024G06FG2020

doi: 10.5348/100024G06FG2020CR

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How to cite this article

Gounain FZ, Malidé A, Mamouni N, Errarhay S, Bouchikhi C, Abdelaziz B. Diabetes and pregnancy with caudal dysgenesis syndrome: A rare congenital malformation about a case and review of the literature. Edorium J Gynecol Obstet 2020;6:100024G06FG2020.

ABSTRACT


Maternal diabetes is associated with an increased risk of congenital anomalies, and congenital malformations are the leading cause of infant mortality in the first year. Caudal dysgenesis (CD) has the strongest association with diabetes, occurring up to 200 times more frequently in infants of diabetic mothers than in other infants. Fetal death can be a very emotional event, which can make the search for determining an etiology difficult. Women with diabetes can have complicated pregnancies through a variety of congenital abnormalities, with heart abnormalities being the most common. We report a case of a 34-year-old diabetic type 2 patient plus term pregnancy admitted to the delivery room with intrauterine fetal death and discovery of CD syndrome. In this case report, we describe the characteristics of this rare congenital malformations related to type 2 diabetes and fetal prognosis.

Keywords: Caudal dysgenesis, Diabetes, Fetal death, Pregnancy

SUPPORTING INFORMATION


Author Contributions

Fatime Zahra Gounain - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Andatia Malidé - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Nisrine Mamouni - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Sanaa Errarhay - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Chahrazad Bouchikhi - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Banani Abdelaziz - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2020 Fatime Zahra Gounain et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.