Edorium Journal of

Gynecology and Obstetrics

 
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Case Report
 
Liveborn baby by ICSI of micro-TESE derived cryopreserved-thawed sperm of non-mosaic Klinefelter syndrome father
Şafak Hatirnaz1, Ebru Hatirnaz2, Murat Bakacak3, Mehmet Sühha Bostanci4, Melahat Atasever5
1MD, Specialist Doctor, Clinart IVF Center, Trabzon, Turkey.
2MD, Doctor, Clinart IVF Center, Trabzon, Turkey.
3MD, Assistant Professor, Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, School of Medicine, Kahramanmaraş, Turkey.
4MD, Specialist Doctor, Department of Obstetrics and Gynecology, Sakarya University Research and Education Hospital, Sakarya, Turkey.
5MD, Assistant Professor, Department of Obstetrics and Gynecology, Giresun University, School of Medicine, Giresun, Turkey.

Article ID: 100001G06SH2015
doi:10.5348/G06-2015-1-CR-1

Address correspondence to:
Murat Bakacak
Kahramanmaras Sutcu Imam Universitesi
Tip Fakültesi, Avsar Kampusu, Merkez
Kahramanmaras
Turkey
Phone: 00903442803739
Fax: 00903442803738

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How to cite this article:
Hatirnaz Ş, Hatirnaz E, Bakacak M, Bostanci MS, Atasever M. Liveborn baby by ICSI of micro-TESE derived cryopreserved-thawed sperm of non-mosaic Klinefelter syndrome father. Edorium J Gynecol Obstet 2015;1:1–4.


Abstract
Klinefelter syndrome (KS) is the most common sex chromosome abnormality in azoospermic males and its prevalence changes in different countries. Until recently KS patients were accepted as sterile however with the impact of microsurgical testicular sperm extraction (micro-TESE) and good freezing modalities healthy pregnancies and live born babies achieved. Klinefelter syndrome males have a wide variety of semen findings from severe azoospermia to nearly normal sperm findings but mostly in the range of azoospermia and severe oligoasthenoteratospermia. For some social and economical reasons, patients decide to have micro-TESE operation first as in this case. The number of publications and case reports has been increasing and implantation rates and clinical outcomes are comparable with the fresh micro-TESE derived sperm used cases. The use of cryopreserved-thawed sperms of KS patients for intracytoplasmic sperm injection (ICSI) could be a choice in especially socioeconomically deprived couples since the implantation rates and clinical outcomes are similar.

Keywords: Cryopreserved-thawed sperms, Klinefelter syndrome, Liveborn baby, micro-TESE


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Author Contributions
Şafak Hatirnaz – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ebru Hatirnaz – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Murat Bakacak – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mehmet Sühha Bostanci – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Melahat Atasever – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2015 Şafak Hatirnaz et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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